PUBLICATIONS

PAPERS SCIENTIFIC MEETINGS

 

Partner publications from the project and on biological effects measures:

Williams, T.D., Gensburg, K., Minchin, S.D. & Chipman, J.K. (2003) A DNA expression array to detect toxic stres response in European flounder (Platicthys flesus) Aquat. Toxicol. 65, 141-158. pdf file of paper. primer list. array image1. array image 2.

Dixon, T.J., Taggart, J., and George, S.G.(2002) Application of real time PCR determination to assess interanimal variablities in CYP1A induction in the European Flounder (Platicthys flesus). Mar. Environ. Res. 50, 267-270. pdf file of paper


Franklin TM, Lee J-S, Kohler A and Chipman JK(2000) Analysis of mutations in the p53 tumour suppressor gene and Ki- and Ha-ras proto-oncogenes in hepatic tumours of European flounder (Platichthys flesus). Marine Env. Res., 50, 251-255.pdf file of paper


George,S.G. & Olssen,P-E. (1994) Metallothioneins as indicators of trace metal pollution, Chapter 7, pp 151-178, In, Biological monitoring of coastal waters and estuaries, K.J.M. Kramer,Ed. CRC Press Inc., Boca Raton FL.


George, S.G. and Langstone, W. (1994) Metallothionein as an indicator of water quality- . Assessment of the bioavailability of cadmium, copper, mercury and zinc in aquatic animals at the cellular level. In, Water quality and Stress indicators in marine and freshwater ecosystems: Linking levels of organisation (Individuals, populations, communities), Ed. D. W. Sutcliffe. Special Publication. The Freshwater Biological Association. Ambleside, UK. ISBN 0-900386-54-1, pp. 138-153


George, S.G., Christiansen, J.S., Killie, B. and Wright, J. (1995) Dietary crude oil exposure induces hepatic mixed function oxygenase, CYP1A activity, at very low environmental temperatures in Polar Cod (Boreogadus saida ) during sexual maturation: validatory studies for Arctic biomonitoring and baseline data for the Barents Sea. Mar. Ecol. Progr. Ser. 122, 307-312.


George, S.G., Wright, J., and Conroy, J. (1995) Temporal studies of the impact of the Braer oilspill on inshore fish from Shetland, Scotland . Arch. Environ. Contam. & Toxicol. 29, 530-534.


Lee J-S, Franklin TM and Chipman JK (2000) Cloning of the b-actin gene from the European Flounder (Platichthys flesus L). DNA sequence, 11: 83-86.

Livingstone,D.R. Forlin,L., and George,S.G.(1994) Molecular biomarkers and toxic consequences of impact by organic pollution in aquatic organisms. In, Water quality and Stress indicators in marine and freshwater ecosystems: Linking levels of organisation (Individuals, populations, communities), Ed. D. W. Sutcliffe. Special Publication. The Freshwater Biological Association. Ambleside, UK. ISBN 0-900386-54-1, pp. 154-171.

Mitchelmore, CL, and Chipman, JK.(1998) DNA strand breakage in aquatic organisms and the potential value of the comet assay in environmental monitoring. Mutation Research 399, 135-147.

Sulaiman,N., George,S. and Burke,M.D.(1991). Sublethal assessment of pollutant impact on flounders in an industrialised estuary using hepatic biochemical indices. Mar. Ecol. Progr. Ser. 68,207-212

Tom, M., Myers, C.R., Waterman M.R. (2001) Competitive ELISA utilizing membrane-free, recombinant fish CYP1A as standard for evaluation of its microsomal homologue molar concentrations. Aquat. Toxicol. 59, 101-114. pdf file of paper.

Tom, M., Jakubov, E., Rinkevich, B. and Herut, B. (1999) Monitoring of hepatic metallothionein mRNA levels in the fish Lithognathus mormyrus - evaluation of transition metal pollution in a Mediterranean coast. Mar. Pollut. Bull. 38: 503-508.

Tom, M., Moran, O., Jakubov, E., Cavari, B., and Rinkevich, B. (1998). Molecular characterization of metallothionein-cDNA of Sparus aurata used for detecting heavy metal pollution along the Mediterranean coast of Israel. Mar. Pollut. Bull. 36: 131-137.


Tom, M., Moran, O., Jakubov, E., Cavari, B., and Rinkevich, B. (1998). Molecular characterization of metallothionein- and cytochrome P4501A -cDNAs of Sparus aurata and their use for detecting pollution along the Mediterranean coast of Israel. In: New Developments in Marine Biotechnology. Plenum Press: 311-314.


Williams, TD, Lee JS, Sheader DL and Chipman JK, (2000) The cytochrome P450 1A gene (CYP1A) from European flounder (Platichthys flesus L.) analysis of regulatory regions and development of a dual luciferase reporter gene system. Marine Env. Res., 50, 1-6. pdf file of paper


PAPERS PRESENTED AT PRIMO 12,

May 9-13 2003,

Safety Harbour, Florida

Plenary #60, Overview of the Genipol project

POLLUTANT RESPONSES IN EUROPEAN SENTINEL FISH SPECIES: A GENOMIC AND PROTEOMIC APPROACH TO BIOLOGICAL EFFECTS DIAGNOSIS: THE GENIPOL PROJECT

 

 

Steve George's presentation

A Poster Overview

Poster of Results Summary

Plenary #61, The Mk1 miniarray

DNA EXPRESSION ARRAYING IN EUROPEAN FLOUNDER (PLATICHTHYS FLESUS)

 

Tim Williams' presentation

Plenary #65

PROTEOMIC ANALYSIS OF POLLUTANT RESPONSES IN EUROPEAN FLOUNDERS; METHODOLOGICAL DEVELOPMENT AND PRELIMINARY ANALYSIS OF EFFECTS OF ESTUARINE POLLUTION.

 

Adelina's presentation given by Steve

Plenary #78

DUAL EVALUATION, OF TRANSCRIPT BIOMARKERS IN THE FISH STRIPED SEA BREAM USING REAL TIME PCR

 

 

Moshe Tom's presentation

Plenary #80

APPLICATION OF REAL TIME PCR FOR QUANTITATIVE DETERMINATION OF HEPATIC VITELLOGENIN TRANSCRIPT LEVELS IN THE STRIPED SEA BREAM.

 

 

 

Bruria Funkestein's presentation

Poster # 290

ISOLATION OF DIFFERENTIALLY EXPRESSED GENES IN CONTAMINANT EXPOSED EUROPEAN FLOUNDER BY SUPPRESSIVE SUBTRACTIVE HYBRIDISATION.

 

 

Derek's poster

Poster #293

A COMPARISON OF METABOLOME, PROTEOSOME AND TRANSCRIPTOSOME RESPONSES IN EUROPEAN FLOUNDERS SUBJECTED TO ESTUARINE POLLUTION

 

 

Steve's poster

   
   

PAPERS PRESENTED AT 22ND ESCPB MEETING, BIOLOGIVAL EFFECTS OF POLLUTANTS: THE ROLE OF ENVIRONMENTAL PROTEOMICS AND GENOMICS, ALESSANDRIA, ITALY, DECEMBER 14-18, 2003

Chipman, J.K.(2003) Toxicogenomics in non-model organisms: development of a DNA array to detect differential gene expression in the european flounder (Platichthys flesus).
Plenary lecture , 22nd ESCPB meeting, Biological effects of pollutants: The role of environmental proteomics and genomics. Alessandria, Italy, Dec. 14-18, 2003. ABSTRACT


George, S.G, Chipman, J.K., Fey, S., Mose-Larson, P., and Tom, M. (2003). A Genomic and Proteomic approach to develop Toxicologically Predictive Gene sets for assessment of fish health in polluted environments. Plenary lecture , 22nd ESCPB meeting, Biological effects of pollutants: The role of environmental proteomics and genomics. Alessandria, Italy, Dec. 14-18, 2003. ABSTRACT


George, S., Dixon, T., Sabine, V., Diab, A., and Taggart, J. (2003) Interindividual variability in expression of xenobiotic metabolising genes in European flounder, Platichthys flesus. Poster presentation, 22nd ESCPB meeting, Biological effects of pollutants: The role of environmental proteomics and genomics. Alessandria, Italy, Dec. 14-18, 2003. ABSTRACT. PDF FILE OF POSTER


George, S.G., Sabine, V., Lyons, B., Gubbins, M., McIntosh, A., Thain, J. and Scott, A. (2003) Biomarker responses of flounder in a polluted estuary: transcriptional responses vs. protein responses as measurement procedures. Round table discussion presentation, 22nd ESCPB meeting, Biological effects of pollutants: The role of environmental proteomics and genomics. Alessandria, Italy, Dec. 14-18, 2003. ABSTRACT


Williams T.D., Sheader D.L., Diab A., Minchin S.D., Lyons B.P., George S.G., Sabine, V. and Chipman J.K. (2003). Identification of pollutant-responsive genes by cDNA microarray with European flounder (Platichthys flesus L.). Poster presentation, 22nd ESCPB meeting, Biological effects of pollutants: The role of environmental proteomics and genomics. Alessandria, Italy, Dec. 14-18, 2003. ABSTRACT. PDF FILE OF POSTER

 

back to top